Daniel L. Rock, Pathology, College of Veterinary Medicine, U of I at Illinois

University of Illinois at Urbana-Champaign

U of I logo College of Veterinary Medicine

Daniel L. Rock

Department Head, Pathobiology
Professor, Pathobiology

Professional Interests:  Viral pathogenesis - molecular mechanisms of viral virulence and host range.  Functional pathogen genomics.

Selected Publications:

Balinsky, C. A., Delhon, G., Smoliga, G., Parat, M., French, R. A., Geery, S. J., Rock, D. L., and Rodriguez.  (2007).  Rapid Preclinical Detetcion of Sheeppox Virus by a Real-Time PCR Assay.  J. Clin. Micro (In Press).

Zaffuto, K. M., Piccone, M. E., Burrage, T. G., Rissatti, G. R., Borca, M. V., Holinka, L. G., Rock, D. L., and Afonso, C. L.  (2007).  Classical Swine Fever Virus Inhibits Nitric Oxide Production in Infected Macrophages.  J. Gen. Virol; 88 (11) 3007-3012.

Carillo, C., Lu., Z., Borca, M. V., Vagnozzi, A., Kutish, G., and Rock, D. L.  (2007).  Genetic and Phenotypic Variation of FMDV During Serial Passages in a Natural Host.   J. Virol; 81 (20) 11341-11351.

Balinksky, C. A., Delhon, G., Afonso, C. L., Risatti, G. R., Borca, M. V., French, R. A., Tulman, E. R., Geary, S. J., and Rock, D. L.  (2007).  Sheeppox Virus Kelch-Like Gene SPPV-019 Affects Virus Virulence.  J. Virol; 81 (20) 11392-11401.

Risatti, G. R., Holinka, L. G., Fernandez Sainz, I., Carillo, C., Kutish, G. F., Lu, Z., Zhu, J., Rock, D. L., and Borca, M. V.  (2007).  Mutations in the Carboxyl Terminal Region of E2 Glycoprotein of Classical Swine Fever Virus Are Responsible for Viral Attenuation in Swine.  J. Virol; 364 (2) 371-382.

Tulman, E. R., Delhon, G., Afonso, C. L., Lu, Z., Zsak, L., Sandybaev, N. T., Kerembekova, U. Z., Zaitsev, V. L., Kutish, G. F., and Rock, D. L.  (2006).  Genome of Horsepox Virus.  J. Virol; 80 (18) 9244-9258.

Delhon, G., Afonso, C. L., Tulman, E. R., Lu, Z., Becnel, J. J., Moser, B. A., Kutish, G. F., and Rock, D.L. (2006).  Genome of Invertebrate Iridescent Virus 3 (Mosquito Iridescent Virus).  J. Virol; 80 (17) 8439-8449

Chang, A. C. Y., Zsak, L., Feng, Y., Mosseri, R., Lu, Q., Kowalski, P., Laegreid, W. W., Rock, D. L., and Cohen, S. N.  (2006).  Phenotype-Based Identification of Host Genes Required for Replication of African Swine Fever Virus.  J. Virol; 80 (17) 8705-8717.

Afonso, C. L., Tulman, E. R., Delhon, G., Lu, Z., Viljoen, G. J., Wallace D. B., Kutish, G. F., and Rock, D. L.  (2006).  Genome of Crocodilepox Virus.  J. Virol; 80 (10) 4978-4991.

Risatti, G. R., Holinka, L. G., Lu, Z., Kutish, G. F., Tulman, E. R., French, R. A., Hyang, Sur J., Rock, D. L., and Borca, M. V.  (2005).  Mutation of E1 Glycoprotein of Classical Swine Fever Virus Affects Viral Virulence in Swine.  J. Virol; 343 (1) 116-127.

Budowle, B., Schutzer, S., Ascher, M. S., Atlas, R. M., Burans, J. P., Chakraborty, R., Dunn, J. J., Franz, D. R., Fraser, C. M., Leighton, T. J., Morse, S. A., Murch, R. S., Ravel, J., Rock, D. L., Slezak, T. R., Velsko, S. P., Walsh, A. C.,  and Walters, R. A.  (2005).  Toward a System of Microbial Forensics: From Sample Collection to Interpretation of Evidence. Applied and Environmental Microbiology; 71 (5) 2209-2213.

Li, J. S., Cui, L., Rock, D. L., and Li, J.  (2005).  Novel Glycosidic Linkage in Aedes Aegypti Chorion Peroxidase:  N-Mannosyl Tryptophan.  J. Biol. Chem; 280 (46) 38513-38521.

Carrillo, C., Delhon, G. A., Tulman, E. R., Lu, Z., Carreno, A., Vagnozzi, A., Kutish, G., and Rock, D.L.  (2005).  Comparative Genomics of Foot-and-Mouth Disease Virus. J. Virol; 79 (10) 6487-6504.

Afonso, C. L., Delhon, G. A., Tulman, E. R., Lu, Z., Zsak, A., Becerra, V. M., Kutish, G. F., and Rock, D. L.  (2005).   The Genome of Deerpox Virus.  J. Virol; 79 (2) 966-977.

Risatti, G. R., Borca, M.V., Kutish, G. F., Lu, Z., Holinka, L.G., French, R. A., Tulman, E., and Rock, D. L.  (2005).  The E2 Glycoprotein of Classical Swine Fever Virus is a Virulence Determinant in Swine.  J. Virol; 79 (6) 3787-3796.

Burrage, T. G., Lu, Z., Neilan, J. G., Rock, D. L, and Zsak, L.  (2004).  African Swine Fever Virus Multigene Family:  360 Genes Affect Virus Replication and Generalization of Infection in Ornithodoros Porcinus Ticks.  J. Virol; 78 (5) 2445-2453.

Neilan, J. G., Zsak, L., Lu, Z., Burrage, T. G., Kutish, G. F., and Rock, D. L.  (2004).  Neutralizing Antibodies to African Swine Fever Virus Proteins, p30, p54, and p72 Are Not Sufficient for Antibody-Mediated Protection.  J. Virol; 319:337-342.

Afonso, C. L., Piccone, M. E., Zaffuto, K. M., Neilan, J. G., Kutish, G. F., Lu, Z., Balinsky, C. A., Gibb, T. R., Bean T. J., Zsak, L., and Rock, D. L.  (2004).  African Swine Fever Virus Multigene Family 360 and 530 Genes Affect Host Interferon Response.  J. Virol; 78 (4) 1858-1864.

Tulman, E. R., Afonso, C. L., Lu, Z., Zsak, L., Kutish, G. F., and Rock, D. L.  (2004).  The Genome of Canarypox Virus. J. Virol; 78 (1) 353-366.

Delhon, G., Tulman, E. R., Afonso, C. L., Lu, Z., de la Concha-Bermejillo, A., Lehmkuhl, H., Piccone, M. E., Kutish, G. F., and Rock, D. L.  (2004).  Genomes of the Parapoxvirus Orf Virus and Bovine Papular Stomatitis Virus.  J. Virol; 78 (1) 168-177.