FRADS - Foot Mouth Disease

Foot-and-Mouth Disease Information:

DEFRA, United Kingdom
Office Internationale des Epizooties FMD
Institute for Animal Health FMD homepage
R.K. Booth / Esh Winning FMD information
The Pig Site information on FMD in swine
USDA APHIS information on FMD and other vesicular diseases

Consultant Foot-and-Mouth Disease:

General

Tongue of infected cow 1 day after intradermahingual inoculation. The raised, round area in the center of the large, white, blanched area is the site of inoculation. The large, white blanched area is a vesicle. If this area is pressed, the upper layers of epithelium will move because they are detached from the deeper layers. This white, blanched tissue can be easily removed using forceps and a scissors and is an excellent specimen for confirming a diagnosis.

Classical FMD causes profuse drooling of frothy material, often mixed with blood and pieces of tissue teeming with virus. This presentation is consistent with oral and foot lesions (erosions, hemorrhages, ataxia, etc.) Control measures include quarantine, slaughter and compensation, and vaccination.

There are seven serotypes of FMDv: A, 0, C, Asia 1, and Southern African Territories (SAT) 1, 2 and 3. Within these serotypes, more than 60 subtypes have been described, and new subtypes occasionally arise spontaneously. At any given time, however, there are only a few subtypes causing disease throughout areas where FMD is endemic. The importance of subtypes is that an FMD vaccine may have to be tailored to the subtype present in the area in which the vaccine is to be used.

TM	University of Illinois at Urbana-Champaign College of Veterinary Medicine Contact: Dr. Kakoma - kakomai@uiuc.edu Phone: 217-333-1859