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Carla Morrow and Dr. Rex Hess

Carla M. K. Morrow, DVM, MS, DABVT

Post-Doctoral Research Associate, Veterinary Bioscience
morrow1@uiuc.edu

SHORT BIO: I grew up on a family farm in northeast Iowa and received both my undergraduate and veterinary degrees from Iowa State University. I practiced small animal medicine in eastern Nebraska for 6 years prior to returning to graduate school for a clinical toxicology residency at the University of Illinois. During my residency, I completed my MS and received my American Board of Veterinary Toxicology certification. I then started work on my PhD with Dr. Rex Hess in male reproductive toxicology. My various research interests include expression and function of estrogen-receptor interacting coregulators in the male reproductive tract and role of the transcription factor ERM in maintaining testes immune privilege and the blood-testes barrier. My husband and I live in Champaign with our 2 cats.

 

EDUCATION

            Iowa State University, College of Agriculture, Ames, IA

            Degree: Bachelor of Science Animal Science, Chemistry minor, May 1990

 

            Iowa State University, College of Veterinary Medicine, Ames, IA

            Degree: Doctor of Veterinary Medicine, May 1994

 

            University of Illinois at Urbana-Champaign, Veterinary Biosciences, Urbana, IL

            Master of Science Veterinary Toxicology, May 2003

            Thesis: “Immunomodulating Effects of Ultraviolet-B Radiation upon Transcutaneous

Immunization in Cattle and Crl:SKH1-hrBR Hairless Mice”

 

            American Board of Veterinary Toxicology: Board Certified Diplomat, August 2003

 

University of Illinois at Urbana-Champaign, Veterinary Biosciences, Urbana, IL

            Doctor of Philosophy, expected December 2007

            Area of Study: male reproductive toxicology        

 

RESEARCH

My research projects during my residency included investigating the effects of ultraviolet radiation upon immune function in mice and cattle and also upon the carcinogenicity of PCBs in hairless mice. These projects were under the direction of Dr. Rhian Cope. I also performed a histological survey with Drs. Ted Valli and Petra Volmer of dogs that died from acute renal failure after eating grapes or raisins. My PhD work with Dr. Rex Hess in male reproductive toxicology has focused on the expression and function of estrogen-receptor interacting coregulators in the male reproductive tract, particularly the co-repressor REA. My current work involves investigating the role of the transcription factor ERM in establishing and maintaining spermatogenesis and also testes immune privilege by using a spermatogonial stem cell transplant model.

 

HONORS & AWARDS

Dr. Loyd E. Boley Award for outstanding performance by a resident studying an AVMA-recognized specialty at the University of Illinois College of Veterinary Medicine; 2001 recipient.  

University of Illinois at Urbana-Champaign Phi Zeta Research Emphasis Day, Basic Science Platform Presentation Competition, April 2004: 3rd place winner.

University of Illinois at Urbana-Champaign Reproductive Biology Training Grant Post-Doctoral Fellowship, July 2004-July 2006.

Dr. Ted and Mrs. Carol Valli Award for Research Performed by a Graduate Student Veterinarian, University of Illinois at Urbana-Champaign College of Veterinary Medicine: 2004 recipient.  

University of Illinois at Urbana-Champaign Phi Zeta Research Emphasis Day, Basic Science Poster Presentation Competition, April 2005: 1st place winner.

National Institutes of Health Contraception and Infertility Research Loan Repayment Program Award: 2005-2007.

University of Illinois at Urbana-Champaing NEIHS Predoctoral Traineeship in Endocrine, Developmental, & Reproductive Toxicology, March 2007-February 2008.

 

PUBLICATIONS (peer reviewed) Total of 7

“Acute renal failure in dogs subsequent to the ingestion of grapes or raisins: a retrospective study of 43 cases (1999-2002)”; P.E. Eubig, M. Brady, S. Gwaltney-Brant, S. Khan, E. Mazzaferro, C. K. Morrow; J Vet Intern Med 19(5):663-674; 2005.  

“Time- and tissue-dependent polychlorinated biphenyl residues in hairless mice after exposure to polychlorinated biphenyl-contaminated soil”; K. Imsilp, L. Wiedenmann, G.O. Bordson, C.K. Morrow, R. Cope, L.G. Hansen; Arch Environ Contam 49(1):105-118, 2005.  

“Canine renal pathology associated with grape or raisin ingestion: 10 cases”; C.M.K. Morrow, V.E. Valli, P.A. Volmer, P.E. Eubig; J Vet Diag Invest 17(3):223-231, 2005.  

“Exposure to soil contaminated with an environmental PCB/PCDD/PCDF mixture modulates ultraviolet radiation-induced non-melanoma skin carcinogenesis in the Crl:SKH1–hrBR hairless mouse”; R.B. Cope, K. Imsilp, C.K. Morrow, J. Hartman, D.J. Schaeffer, L.G. Hansen; Cancer Letters 191:145-154; 2003.  

“Ultraviolet radiation enhances both the nodular and ulcerative forms of Mycobacterium ulcerans infection in a Crl:IAF(HA)-hrBR hairless guinea pig model of Buruli ulcer disease”; R.B. Cope, J.A. Hartman, C.K. Morrow, W.M. Haschek, P.L. Small; Photodermatol Photoimmunol Photomed 18:271-279; 2002.  

“Simulated Solar UVB Exposure Inhibits Transcutaneous Immunization to Cholera Toxin in Cattle”; C.K. Morrow, I.G. Colditz; R.B. Cope; Vet Immunol Immunopathol 83:107-114; 2001.  

“Analysis of Gait Parameters in Duroc Swine Genetically Divergent for Front-Leg Structure”; C.M. Kehret-Morrow, M.F. Rothschild, D.D. Draper, L.L. Christian. J Anim Breed Genet 108:280-289; 1991.  

Invited Lectures/Seminars

“Overview of Canine Grape Toxicosis”: C.K. Morrow, E. Mazzoferro, P.E. Eubig, P.A. Volmer, S. Gwaltney-Brant; Veterinary Information Network Online Veterinarian Rounds, vin.com, August 2005.

“Human Medications: Part I”: C.K. Morrow; Continuing Education Seminar; Small Animal Toxicology Short Course, University of Illinois, Urbana, IL; March, 2002.

“Dealing with the Poisoned Pet”; C.K. Morrow, P.A. Volmer; Continuing Education Seminar; 82nd Annual Fall Conference for Veterinarians, University of Illinois, Urbana, IL; October, 2001.

 

Abstracts
“Expression of Estrogen receptor (ER) Interacting Nuclear Receptor Cofactors in Mouse Testes”: C. Morrow, K. Carnes, J. Ford, S.-E. Park, B.S. Katzenellenbogen, R.A. Hess; Society for the Study of Reproduction 39th Annual Meeting; Omaha, NE; July 2006.

“Male Reproductive Abnormalities in Repressor of Estrogen Receptor Activity (REA) Heterozygous Knockout Mice”: C. Morrow, S.-E. Park, M. Mukai, B.S. Katzenellenbogen, R.A. Hess; Oral Presentation; American Society for Andrology 31st Annual Meeting; Chicago, IL; April 2006.

 

“Nuclear Receptor Cofactors in Efferent Ductules of Mouse, Rat, Hamster, and Monkey”; C. Morrow, K. Carnes, C. Oliveira, J. Ford, T. Phillips, B.S. Katzenellenbogen, R.A. Hess; Poster Presentation; American Society for Andrology 30th Annual Meeting; Seattle, WA; April 2005.

 

“Canine Renal Pathology Associated with Grape or Raisin Ingestion: 10 Cases”: C.K. Morrow, V.E. Valli, P.A. Volmer, P.E. Eubig; Oral Presentation; American Association of Veterinary Laboratory Diagnosticians Annual Meeting, San Diego, CA; October, 2003.

 

“UV Pre-Exposure Increases the Severity of Mycobacterium ulcerans Infection in a Hairless Guinea Pig Model of Buruli Ulcer Disease”; R.B. Cope, J.A. Hartman, C.K. Morrow, W.M. Haschek, P.L. Small; Oral Presentation; 83rd Annual Meeting Conference for Research Workers in Animal Disease, St. Loius, MO; November, 2002.

 

“Does an Environmental PCB/PCDF Mixture Enhance Ultraviolet Radiation-Induced Skin Cancer?”; C.K. Morrow, K. Imsilp, L.G. Hansen and R.B. Cope; Oral Presentation; 30th Annual Meeting American Society for Photobiology, Quebec City, Canada; July 2002.

“Immunomodulating Effects of Ultraviolet-B radiation on Transcutaneous Immunization in Cattle and Hairless Mice”; C.K. Morrow, R.B. Cope; Oral Presentation; 82nd Annual Meeting Conference for Research Workers in Animal Disease, St. Loius, MO; November, 2001.

“UVB Exposure Modulates Transcutaneous Immunization to Cholera Toxin at a Non-Irradiated Skin Site”; R.B. Cope, C.K. Morrow; Poster Presentation; 29th Annual Meeting of the American Society for Photobiology, Chicago, IL; July, 2001.

 

Book Chapters and Other Publications

“Cholecalciferol Toxicosis”; C.K. Morrow, P.A. Volmer, in Clinical Veterinary Toxicology, ed. K. Plumlee; Mosby, St. Louis, MO; 2004.

“Hypercalcemia, Hyperphosphatemia, and Soft-Tissue Mineralization”; C.K. Morrow, P. A. Volmer; Compendium 24(5):380-388; May 2002.

“Toxicology Brief: Cholecalciferol Poisoning”; C.K. Morrow; Vet Med 96(12):905-911; December, 2001.


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